Transparency
Market Research Reports incorporated a definite business overview and
investigation inclines on “Primary
Systemic Amyloidosis Market”.
This report likewise incorporates more illumination about fundamental
review of the business including definitions, requisitions and
worldwide business sector industry structure. Amyloids are the
substance made up of abnormally formed protein in the bone marrow
that gets saturated in different tissues or organs of the body. The
condition is termed as amyloidosis. There are various types of
amyloidosis out of which primary systemic amyloidosis are most
common, these are associated with plasma cell dyscrasia and has no
historical evidence of disease. Kidney, intestines, liver, heart and
nerves are the common organs where amyloids get deposited and result
in various localized complications. Deposition of amyloids in the
heart causes continuous progression towards heart failure by
cardiomyopathy, accumulation of amyloids renal system causes renal
dysfunction and hepatomegaly can happen because of amyloids
infiltration in the liver. Generally diagnosis of this disease is
delayed because of no specific symptoms associated with it; however,
some symptoms associated with disease include severe fatigue with
weakness, feeling of satiety every time, difficulty in swallowing,
swelling of tongue. There are several tests used for diagnosis of
primary systemic amyloidosis depending on the organ affected, out of
which Urinalysis, whole blood count, test for high creatinine level
and liver function test are common.
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Though
primary systemic amyloidosis is very rare disease but it has spread
across the world. According to article published by American Society
of Nephrology (ASN), it is estimated that around five to twelve
people per million per year are affected by primary systemic
amyloidosis. At the same time, several numbers of cases of this
disease remain undiagnosed. The scenario is similar in all regions of
the world. All these facts represent significant demand of the
various treatment options for primary systemic amyloidosis globally.
The investment in research and development, suitable reimbursement
conditions and advancements in diagnosis technologies may drive the
growth of the market. On the other hand high cost involved in
treatment and limited awareness may hinder the growth of the overall
market. Currently there are many research projects under study that
are focused on advancement in the treatment of primary systemic
amyloidosis. Celgene Corporation in collaboration with Italian
institute Fondazione I.R.C.C.S. - Policlinico San Matteo studying the
use of of cyclophosphamide, lenalidomide and dexamethasone for
previously treated patients with primary systemic amyloidosis, Boston
University evaluating the safety and effect of doxycycline in
patients with amyloidosis, French Nantes University Hospital studying
the effect of lenalidomide in combination with melphalan and
dexamethasone in newly-diagnosed patients, National Cancer Institute
(NCI) in collaboration with Mayo Clinic using evaluating the use of
lenalidomide, cyclophosphamide, and dexamethasone in treating
patients with primary systemic amyloidosis.
Primary
systemic amyloidosis market can be segmented according to different
categories such as regional geography and available treatment
options. Geographically, this market can be segmented in four regions
namely North American, Europe, Asia-Pacific and Rest of the World,
out of all these segments North America region will have highest
contribution in terms of value because of high awareness, higher
percentage of total income spent on healthcare compared to other
economies and appropriate reimbursement circumstances. Followed by
this, Europe, Asia-Pacific and Rest of the World respectively could
be major segments of the market. The market can also be segmented
according to treatment options such as enzyme inhibitors, immune
modulators, diuretics and others. The market can be divided according
to symptomatic therapies.
Currently
many established players in pharmaceuticals and biotechnology market
catering varied range of products in this market. Out of these
companies, Prothena Corporation plc, Celgene Corporation and Onclave
Therapeutics Limited Llc are leading contributors.
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This
research report analyzes this market depending on its market
segments, major geographies, and current market trends. Geographies
analyzed under this research report include
- North America
- Asia Pacific
- Europe
- Rest of the World
This
report provides comprehensive analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
- Market projections for upcoming years
This
report is a complete study of current trends in the market, industry
growth drivers, and restraints. It provides market projections for
the coming years. It includes analysis of recent developments in
technology, Porter’s five force model analysis and detailed
profiles of top industry players. The report also includes a review
of micro and macro factors essential for the existing market players
and new entrants along with detailed value chain analysis.
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Market Research is a market intelligence company providing global
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quantitative forecasting and trends analysis provides forward-looking
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